Low Dose Naltrexone (LDN) has taken healthcare by storm in the last 10 years.
Low Dose Naltrexone is commonly mistaken as Naltrexone, by patients and medical providers alike. Naltrexone was approved by the FDA in the mid-1980s for drug and alcohol addiction. Naltrexone as prescribed for alcohol addiction is in dosages of 50 mg - 300 mg. Low Dose Naltrexone (LDN) is approximately 1/10th of the typical treatment dosage of Naltrexone. In most published research, the daily dosage is 4.5 mg, though the dosage can vary a few milligrams below or above that common value.
How does LDN work?
When Naltrexone is taken in small doses it blocks opioid receptors, it is believed to up-regulate vital elements of your immune system by increasing your body’s production of endorphins, hence Low Dose Naltrexone improves immune system function.
LDN also turns on your ‘T Regulatory’ cells. These cells make sure that inflammatory chemicals are secreted appropriately to help you when injured and then to halt your inflammation when you are healed.
ie. LDN increases the production of endorphins improving the immune system while decreasing pain and inflammation and increasing a sense of well being.
What does LDN help?
If you suffer from an autoimmune disorder (Multiple Sclerosis, Crohn’s, Hashimoto’s, Thyroid, Fibromyalgia, Lupus, etc.), cancer, tumors you will want to speak to your doctor about adding LDN to your treatment plan. Although completed studies are limited, there are long-term studies in progress, as well as plenty of anecdotal evidence that LDN makes a significant difference in peoples lives that suffer from a wide range of disorders.
Here are a few conditions that are helped from LDN:
- Lyme’s Disease
- Anxiety & Depression
- Inflammatory Bowel Disease (IBD)
- Hashimoto’s Thyroiditis
- Grave's Disease
- Chronic Fatigue Syndrome (CFS)
- Crohn’s disease
- Multiple Sclerosis (MS)
- Rheumatoid Arthritis (RA)
- Ulcerative Colitis (UC)
- Concussion Syndrome
- Migraine Headaches
- Neuropathy / Nerve Pain
- Weight Loss
- ….and more
Side Effects of the Medication
Low Dose Naltrexone has proven to have minimal (if any) side effects, but like any other pill or supplement you take, side effects are possible. Some side effects may be anxiety, headaches, insomnia, vivid dreams or difficulty sleeping.
Low Dose Naltrexone and the FDA
LDN is not approved by the FDA for autoimmune conditions, which means it is not commercially available. For that reason, you need to have a compounding pharmacy fill your prescription.